Filter results by document type and/or working area to find what you're searching for.
This case study has been kindly provided and compiled by Priv.-Doz. Dr Mathias Zimmermann and describes results of a patient with a suspected diagnosis of a systemic bacterial infection with clear signs of infection over a course of time. Delta-He, the difference between the haemoglobin content of the newly-formed reticulocytes (RET-He) and the haemoglobin content of the mature red blood cells (RBC-He) is usually positive in healthy people but turns negative within a few hours due to inflammation as there is an iron deficiency. Also, the ICIS (Intensive Care Infection Score), an RUO application on Extended IPU, gives some interesting insights in this example case.
This white paper intents to give an overview of the most common types of anaemia with a focus on how haematological parameters such as RET-He and other advanced RBC parameters could help to distinguish different causes of anaemia. The white paper also summarises current guidelines and publications on advanced RBC parameters.
Haemostasis is a complex process that helps to keep the blood in a fluid state and prevent blood loss at the site of injury. While the intact endothelium of blood vessels has an anti-thrombogenic function that prevents blood coagulation, in the case of vessel wall damage, the exposed sub-endothelial components initiate the formation of a clot that will stop blood loss.
The detection of blast cells in the peripheral blood is considered extremely important, and great responsibility is placed on the investigating laboratory. As well as informa¬tion on the physiology, this SEED article describes the possible causes of the release of blast cells into the blood, the char¬acteristics by which they can be identified and how further diagnosis is carried out.
With this clinical case report an example of a rare blastic plasmacytoid dendritic neoplasm (BPDCN) as it occurred on the XN-Series analyser is described. The measurements were carried out directly after treatment and three months later. The distribution of WBC in the WDF scattergrams were abnormal and the XN analyser indicated these abnormalities with the flags ‘Blasts?’ and ‘Abn Lympho?’ and the subsequent manual smear review revealed the presence of blasts.
This SEED article is meant to explain the findings focused on cell count and differentiation for pleural, ascitic, cerebrospinal and synovial fluid as well as for CAPD. Traditionally, body fluid counts are performed by manual counting under a microscope using a haemocytometer, but laboratories now have the option of automating their manual processes using automated haematology or urinalysis analysers. This SEED summarises the advantages and disadvantages of haemocytometry and Sysmex analysers and explains briefly the XN-BF mode.