Scientific Images

Mantle cell lymphoma infiltrating bone marrow
<p>Bone marrow histology (Gomori stain) of a patient showing an infiltration of mantle cell lymphoma cells and an increase in fibres (black lines).</p>

May-Hegglin anomaly
<p>May-Hegglin anomaly belongs to a family of macrothrombocytopenias characterised by mutations in the MYH9 gene. It is a rare autosomal dominant disorder characterised by various degrees of thrombocytopenia that may be associated with purpura and bleeding. </p>

Metamyelocyte
<p>Cell description:
</p>
<p>Size: 10-12 µm
</p>
<p>Nucleus: kidney or U-shaped with clumped chromatin
</p>
<p>Cytoplasm: acidophilic
</p>
<p>neutrophil: fine reddish granulation
</p>
<p>Cell division is not possible anymore and protein synthesis has stopped.</p>

Modified morphology of cells
<p>Blood film prepared after storage of the EDTA blood for more than one day. A safe morphological differentiation is no longer possible.</p>

Monocyte
<p>Cell description:
</p>
<p>Size: 20 µm
</p>
<p>Nucleus: kidney- to band-shaped
</p>
<p>Cytoplasm: grey and clear with fine azurophilic granules
</p>
<p>They are shortly located in the peripheral blood and then move into the tissue where they differentiate into macrophages. Function: Phagocytosis either of harmful pathogens or dead, dying or damaged cells from the blood. </p>

Myeloblast
<p>The first microscopically identifiable cell of granulocytic cell line.
</p>
<p>Cell description:
</p>
<p>Size: 12-20 µm
</p>
<p>Nucleus: large, round or slightly oval with diffuse chromatin pattern and often 1-5 nucleoli
</p>
<p>Cytoplasm: pale blue and usually agranular, sometimes Auer rods visible</p>