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Follicular lymphoma (FL) is the most common form of indolent lymphoma in the western world, accounting for approximately 25% of malignant lymphomas (Ciabanu et al 2013). Disease progression of FL is often unpredictable with 25% - 30% of FL cases progressing; most commonly to diffuse large B cell lymphoma, Hodgkin lymphoma, Burkitt lymphoma and rarely B-lymphoblastic leukaemia/lymphoma (B-ALL) (Swerdlowetal, 2017).
This clinical case reports the disease progression of a patient hospitalised due to a SARS-CoV-2 infection. The patient’s condition worsens significantly over time, ultimately leading to the development of an acute respiratory distress syndrome (ARDS), a common but very severe complication in respiratory tract infections (such as COVID-19).
Determining the aetiology of thrombocytopenia is of major importance. The immature platelet fraction (IPF) can help you promptly differentiate between ineffective bone marrow production and increased destruction or consumption of platelets. Find out more about the use of this parameter here.
Being diagnosed with haematologic malignancy actually happens either because the patient presents with certain symptoms or – as is becoming increasingly common – there are incidental findings during routine blood screening on modern haematology analysers. This white paper aims to describe how parameters of a complete blood count may reveal significant abnormalities and improve the incidental findings of suspected haematologic samples early on.
Chronic kidney disease (CKD) is a severe complication in context of various civilisation diseases, such as diabetes, hypertension, and obesity. With increasing treatment cost along the progression of CKD towards end-stage renal failure (ESRF) and the need for renal replacement therapies, CKD is not only a driver of premature mortality and diminished quality of life of affected individuals, but also puts significant burden on the society and healthcare expenditures. The early detection of kidney damage through a frequent screening of risk patients could help to fight the burden of CKD. Cost-efficient routine urinalysis data could play a vital role in providing valuable information for screening, diagnosing, and monitoring of renal disorders.
This clinical infromation card explains functional iron deficiency (FID) and the advantages of the parameter RET-He (reticulocyte haemoglobin equivalent) as it reflects the the iron availability for haemoglobination in the bone marrow in real-time. A patient case illustrates how RET-He helps to monitor the iron availability at diagnosis and during treatment of FID.