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- White Paper
Advanced RBC parameters in the differential diagnosis and management of anaemia
This white paper intents to give an overview of the most common types of anaemia with a focus on how haematological parameters such as RET-He and other advanced RBC parameters help to distinguish different causes of anaemia. The white paper also summarises current guidelines and publications on advanced RBC parameters in order to help clinicians in choosing the appropriate treatment for the individual patient.
Haemostasis is a complex process that helps to keep the blood in a fluid state and prevent blood loss at the site of injury. While the intact endothelium of blood vessels has an anti-thrombogenic function that prevents blood coagulation, in the case of vessel wall damage, the exposed sub-endothelial components initiate the formation of a clot that will stop blood loss.
- Xtra Article
Counting of highly fluorescent lymphocytes (HFLC) as antibody-producing plasma cells on XE-5000
Besides the IG there is a distinct separation of an abnormal cell population with high fluorescence intensity above the monocyte and lymphocyte region. Highly fluorescent lymphocyte cells (HFLC) are observed in the DIFF channel of the Sysmex XE-series haematology analysers in an area of high fluorescence intensity.
- White Paper
Differential diagnosis of thrombocytopenia
Determining the aetiology of thrombocytopenia is of major importance. The immature platelet fraction (IPF) can help you promptly differentiate between ineffective bone marrow production and increased destruction or consumption of platelets. Find out more about the use of this parameter here.
- White Paper
Early identification of haematologic malignancies using a complete blood count
Being diagnosed with haematologic malignancy actually happens either because the patient presents with certain symptoms or – as is becoming increasingly common – there are incidental findings during routine blood screening. This white paper describes how a complete blood count measured on Sysmex XN-Series analysers may reveal significant abnormalities and improve the incidental findings of haematologic malignancies or the relapse of cancer under treatment early on.
- Diagnostic Perspectives
Fighting for fair competition: blood doping – a persistent challenge and smart approaches to detect it
Doping with blood, erythropoietin or related substances is an unfair practice in sports and is performed to obtain an advantage over competing athletes. Doping control has made great progress in detecting the use of forbidden substances by employing completely new strategies that no longer rely on the detection of the banned substance itself. What is measured instead are the changes that forbidden doping practice has on haematological parameters.