Filter results by document type and/or working area to find what you're searching for.
The fluorescence technology and channel-specific reagents of the XN-Series provide much more than just a cell count. Depending on their cell membrane composition, cells are perforated and labelled differently, disclosing information about the cells’ activity, maturity stage, and malignancy. This white paper sheds a light on how the XN measures cell functionality.
Once the analysis results have been technically validated and considered reliable, they can be looked at from a clinical angle to search for suspect results. The task of biomedical validation is to recognise abnormal or conspicuous quantita¬tive results. Based on the findings compiled by the GFHC, there is a new rule set implemented in Extended IPU looking at things such as cut-off values, assessment of previous values or additional patient information. Check out the recommendation from GFHC.
Unser Poster zeigt die Hämatopoese aus blutzellbildenden Stammzellen nach Ceredig R et al. Nat Rev Immunol 2009, 9(4): 293–300. Die Darstellung der Hämatopoese als Modell des „Sonnensystems“ basiert auf der Idee der hohen Flexibilität und der engen Beziehung zwischen den verschiedenen Arten von Vorläuferzellen. Viele Vorläufer haben gemeinsame Transkriptionsfaktoren. Anstelle einer klassischen Baumdarstellung der Hämatopoese schlagen Ceredig R et al. diese Darstellung vor, um die invarianten paarweisen Entwicklungsbeziehungen zwischen den verschiedenen hämatopoetischen Linien zu zeigen.
In this case report laboratory results of a two-year-old patient presented at the hospital with watery stool (later bloody stool with fever appearing) are shown. The CBC measured on XR-Series showed leucocytosis, anaemia, thrombocytopenia and schistocytes. Further test results revealed acute kidney injury, elevated lactate dehydrogenase (LD), an increase in C-reactive protein (CRP) and antibodies to Escherichia coli O157 lipopolysaccharide were found as well. This led to the suspicion of haemolytic uraemic syndrome due to Shiga toxin-producing E. coli.
Urinary tract infections (UTI) belong to the most common bacterial infections and, though suspected cases often turn out to be negative, contribute to high laboratory workloads and empiric prescription of antibiotics, a main driver antimicrobial resistance (AMR). This white paper reviews the strengths of the UF-series in ruling-out UTI, supporting its diagnosis and potential applications to further optimise the UTI laboratory workflow, aiming to fight AMR.
This case study explains how the same lymphocytes react in two different complementary methods: fluorescence flow cytometry in the WPC channel of the XN-Series haematology analyser and multicolour immunophenotyping using the XF-1600 analyser. The haematology analyser detected a lymphocytosis and a suspect flag for ‘Abnormal Lympho?’. Subsequently, clinical flow cytometry was performed and the markers confirmed the diagnosis of a B-CLL in this patient.
The immature platelet count (IPF#) is a new haematological diagnostic parameter available from a routine blood laboratory test. Discover in this white paper how it can help you to evaluate the effectiveness of antiplatelet medication and forecast the risk of adverse cardiovascular events.